Penja Avui em semble interessant aquesta notícia the web on els Avencas that s'est produint in the investigation de l'autism. The autistic Desenvolupament d'un animal (In this case a rat) will cause researchers to better understand the brain of autistic children, and thus improve treatment of these children. Then upload the news
DESARROLLAN the first animal AUTISTIC
THROUGH the introduction of a genetic mutation Raton, a group of researchers has created the first accurate model Autism in an animal, according to the meeting have submitted annual American College of Neuropsychopharmacology . This animal model can
entails a huge one that the Help for researchers better understand abnormal brain function human beings autism spectrum disorders (ASD), and improve treatment strategies.
People with classical autism show different types of symptoms: impaired social interaction, problems with verbal communication, etc ... The characteristics of autism usually appear during the first three years of childhood and continue throughout life. Although there is no cure, proper care can foster relatively normal development and reduce behavior deemed inappropriate. People with autism have a normal life expectancy.
These behaviors are given by a series various neuropsychiatric disorders, the most important with Fragile X syndrome and Rett syndrome , which are the two conditions that have resulted in genetically modified mice. "With this research, we study the changes in the brain that lead to autistic behaviors, and this may help us understand more about the progression and treatment of disorders," says Craig M. Powell, a neurologist and psychiatrist at the University of Texas .
For these mice, the researchers replaced 3 normal genes by 3 genes associated with autism in humans, getting a mouse with autism very similar to humans. In fact, this small change is very similar to what occurs naturally in some patients. Dr. Powell watched as these mice reflected clear signs of autism, a reduction in social interaction with other mice and anxiety. Coordination and pain sensitivity, were unaffected.
addition, mice showed a greater capacity for spatial learning, which may seem to increase cognitive ability, as seen in human cases, people who have severe mental or developmental disabilities but extraordinary mental abilities. The probably most famous case, dubbed "Rain Man" in honor of the film .
entails a huge one that the Help for researchers better understand abnormal brain function human beings autism spectrum disorders (ASD), and improve treatment strategies.
People with classical autism show different types of symptoms: impaired social interaction, problems with verbal communication, etc ... The characteristics of autism usually appear during the first three years of childhood and continue throughout life. Although there is no cure, proper care can foster relatively normal development and reduce behavior deemed inappropriate. People with autism have a normal life expectancy.
These behaviors are given by a series various neuropsychiatric disorders, the most important with Fragile X syndrome and Rett syndrome , which are the two conditions that have resulted in genetically modified mice. "With this research, we study the changes in the brain that lead to autistic behaviors, and this may help us understand more about the progression and treatment of disorders," says Craig M. Powell, a neurologist and psychiatrist at the University of Texas .
For these mice, the researchers replaced 3 normal genes by 3 genes associated with autism in humans, getting a mouse with autism very similar to humans. In fact, this small change is very similar to what occurs naturally in some patients. Dr. Powell watched as these mice reflected clear signs of autism, a reduction in social interaction with other mice and anxiety. Coordination and pain sensitivity, were unaffected.
addition, mice showed a greater capacity for spatial learning, which may seem to increase cognitive ability, as seen in human cases, people who have severe mental or developmental disabilities but extraordinary mental abilities. The probably most famous case, dubbed "Rain Man" in honor of the film .
can not be said now begins a process of testing these mice to test their response to different drugs, with the important to find a possible solution to this disease.
Source: Physorg
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